Severe aortic stenosis (AS) is increasing in frequency as the population ages. For a subset of patients in whom surgical conventional aortic valve replacement is excluded due to severe co-morbidities, an alternative to surgical aortic valve replacement transcatheter aortic valve replacement (TAVI)- has emerged with a first-in-man case performed in France in 2002 by Pr. Alain Cribier. Since 2002, TAVI has undergone many modifications from first generation devices, and the technique is now performed routinely in selected centres to treat patients with symptomatic severe aortic stenosis who are ineligible or at high-risk for conventional surgical aortic valve replacement. Two transcatheter heart valves, the "Edwards Sapien valve" and the Medtronic Corevalve" are available in Europe. More than 30,000 procedures have been performed worldwide in the last decade.
Gender differences in clinical presentation and outcome of transcatheter aortic valve implantation
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Hemodynamic results after Transcatheter Aortic Valve Implantation (TAVI)
Since 2007 Transcatheter Aortic Valve Implantation (TAVI) has become an alternative treatment for elderly patients with severe aortic stenosis at high risk for surgical aortic valve replacement. At present, durability and hemodynamic performance of transcatheter aortic valves remain unclear. Our single center data of the German Heart Center in Munich demonstrates a sustained improvement of hemodynamic performance up to 3 years after CoreValve implantation.
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Study examines risk of aortic complications among patients with common congenital heart valve defect
While the incidence of the life-threatening condition of aortic dissection is significantly higher than in the general population, it remains low among patients with the congenital heart defect, bicuspid aortic valve; however, the incidence of aortic aneurysms is significantly high, according to a study in the September 14 issue of JAMA.
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Expandable prosthesis resolves advanced aortic valve disease
Among individuals 65 years and older, as many as 30 percent have aortic valve sclerosis or stenosis and as a result of their deteriorating health, they cannot enjoy a normal lifestyle.
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Quality of life benefits of transcatheter aortic valve replacement differ by access site
Results of the PARTNER Cohort A QOL study demonstrate that transcatheter aortic valve replacement (TAVR) results in improved quality of life compared with surgical valve replacement, but only when performed via the transfemoral approach. The results of the study were presented today at the 23rd annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation.
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Results of the PARTNER Trial Cohort A cost effectiveness analysis reported
The cost effectiveness of transcatheter aortic valve implantation (TAVR) compared to surgical aortic valve replacement (SAVR) depends on whether TAVR is performed via the femoral artery or transapically, through a small incision in the chest, according to a new study.
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Results of the STACCATO Trial reported at TCT 2011
Researchers leading a clinical trial said that transapical transcatheter aortic valve implantation (a-TAVI) may be inferior to surgical aortic valve replacement (SAVR) in operable elderly patients. However results were only preliminary as the trial was carried out on 70 patients out of a planned 200 before it was terminated early for safety concerns. Results from the STACCATO trial were presented today at the 23rd annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation.
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New scanning strategy could help develop heart disease treatments
Patients with life-threatening heart valve disease could be helped with alternative scanning techniques that provide greater insight into the condition.
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EAE/ASE 3D echocardiography image acquisition recommendations
For the first time, a joint committee of the European Association for Echocardiography and the American Society of Echocardiography have issued recommendations on image acquisition using three-dimensional echocardiography (3DE). 'The EAE/ASE Recommendations for Image Acquisition and Display Using Three-Dimensional Echocardiography', are available in the January 2012 issue of the Journal of the American Society of Echocardiography (JASE), published by Elsevier.
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UofL physicians, Jewish Hospital first in Kentucky to offer new aortic valve replacement
Some individuals with severe aortic stenosis also known as narrowing of the aortic valve in the heart who are not well enough to undergo open heart surgery have a new treatment option thanks to a new procedure now available in Kentucky from University of Louisville physicians at Jewish Hospital.
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ACCF/AATS/SCAI/STS release consensus document to help guide use of minimally invasive heart therapy
With the U.S. Food and Drug Administration's recent approval of transcatheter aortic valve replacement (TAVR) for patients with aortic valvular stenosis, the American College of Cardiology Foundation (ACCF), along with the American Association for Thoracic Surgery (AATS), the Society for Cardiovascular Angiography and Interventions (SCAI) and the Society of Thoracic Surgeons (STS), today released an expert consensus document to provide important guidance on its use.
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Tavi study shows low mortality rate, improvement in function at 30 days
Patients who underwent transcatheter aortic valve implantation (TAVI) at experienced medical centers had significant improvement in valve function as well as low mortality and stroke rates at 30 days, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session. The Scientific Session, the premier cardiovascular medical meeting, brings cardiovascular professionals together to further advances in the field.
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Long-term outcomes of TAVI show non-cardiac co-morbidities main cause of mortality
Non-cardiac co-morbidities such as chronic obstructive pulmonary disease, chronic kidney disease and frailty are the main predictors of late mortality after transcatheter aortic valve implantation (TAVI), suggesting that patients with these conditions merit closer evaluation and follow-up, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session. The Scientific Session, the premier cardiovascular medical meeting, brings cardiovascular professionals together to further advances in the field.
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Heart patients do better with non-surgical valve replacement than standard medical therapy
Patients diagnosed with aortic stenosis who are too sick for open-heart surgery have better survival rates and an improved quality of life after undergoing catheter-based heart valve replacement than if the patients had been treated with standard medical therapy, according to a study authored by a Cedars-Sinai Heart Institute physician based on results from a multicenter clinical trial.
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Catheter-placed heart valve shows strong performance at two years
Two-year data show comparable death and durability for catheter-placed heart valves and open-heart surgery in very old and ill patients, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session. The Scientific Session, the premier cardiovascular medical meeting, brings cardiovascular professionals together to further advances in the field.
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Transcatheter aortic valve implantation shows promise in patients with severe aortic stenosis
German researchers report success with transcatheter aortic valve implantation (TAVI) in patients with low-flow, low-gradient aortic stenosisa special form of aortic stenosis that is difficult to treat. Results published in the April issue of Catheterization and Cardiovascular Interventions, the peer-reviewed journal of the Society for Cardiovascular Angiography and Interventions (SCAI), show that while all-cause mortality was high within the first six months, TAVI significantly improved heart function and exercise capacity in surviving patients.
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One-fifth of healthy middle-aged men have low-grade murmur
(HealthDay) -- More than one-fifth of healthy middle-aged men have a low-grade systolic heart murmur that confers a nearly five-fold higher risk of future aortic valve replacement (AVR), according to a study published in the June issue of the Journal of Internal Medicine.
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Northwestern launches comprehensive program for patients with bicuspid aortic valve disease
Bicuspid aortic valve (BAV) disease is the most common congenital heart defect, occurring in approximately one to two percent of the population. The condition is present when the aortic valve, the valve that connects the heart to the main artery that distributes blood to the body, contains two leaflets instead of three, which open and close to regulate blood flow. As a result, the valve does not function properly, which can cause strain on the heart over time and may lead to serious health complications. Northwestern Memorial Hospital's Bluhm Cardiovascular Institute (BCVI) has been at the forefront of BAV research and treatment for years and recently launched a comprehensive program that brings together a multidisciplinary team of specialists experienced in the diagnosis and medical and surgical management of patients with BAV.
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UCLA uses new device to replace aortic valve in patients who can't have open-heart surgery
(Medical Xpress) -- UCLA has performed its first transcatheter aortic valve replacement (TAVR), using a new device approved by the U.S. Food and Drug Administration to replace an aortic valve in a patient who was not a candidate for open-heart surgery. The procedure took place on Aug. 9.
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Which valve disease treatment—TAVI or conventional valve replacement—is best for which patient
The German Aortic Valve Registry (GARY) was started in July 2010 and is the only registry so far to include both transcatheter aortic valve implantation (TAVI) and conventional aortic valve replacements and repair.(1) The intention is to deliver a complete picture of current and future practice of treating aortic valve disease and to deliver reliable data on the short and long-term outcome of different treatment strategies. This specifically includes data about quality of life before and after treatment besides numerous medical variables.
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