Two-year data reveal no difference in the combined rate of stroke and death from any cause when comparing the use of self-expanding transcatheter aortic valve replacement (TAVR) with standard open-heart surgery in intermediate risk patients with severe aortic stenosis, according to research presented at the American College of Cardiology's 66th Annual Scientific Session. Researchers say these results suggest TAVR, which involves threading a replacement valve through a catheter in the groin or chest, is at least as safe and effective as surgery in these patients.
Self-expanding TAVR as good as surgery in intermediate-risk patients
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Embol-X and CardioGard do not reduce overall number of brain lesions, but may affect lesion size
Two FDA-cleared medical devices designed to remove potential vessel-blocking debris particles from the bloodstream during aortic valve replacement, known as Embol-X and CardioGard, did not significantly reduce overall number of brain infarcts over standard surgical procedure, according to a study presented at the American College of Cardiology's 66th Annual Scientific Session.
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Heart procedure linked with bleeding in the brain, neurological impairment
Small leakages from blood vessels in the brain, known as microbleeds, increase with age and are associated with cognitive decline. Of 84 older patients undergoing transcatheter aortic valve replacement (TAVR), nearly a quarter developed new microbleeds after their procedure, according to results of a single-center study presented at the American College of Cardiology's 66th Annual Scientific Session.
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CT scans reveal reduced leaflet motion after aortic valve replacement
About 12 percent of patients undergoing aortic valve replacement developed non-symptomatic blood clots around the valve leaflets (known as subclinical leaflet thrombosis) that reduced the motion of the valves, according to an observational study presented at the American College of Cardiology's 66th Annual Scientific Session.
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Conscious sedation is a safe alternative to general anesthesia for heart valve procedure
UCLA scientists have found that conscious sedation—a type of anesthesia in which patients remain awake but are sleepy and pain-free—is a safe and viable option to general anesthesia for people undergoing a minimally invasive heart procedure called transcatheter aortic valve replacement.
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Analysis shows increased risk of early stroke with new-onset atrial fibrillation post-TAVR
More than one-third of patients undergoing transcatheter aortic valve replacement (TAVR) were observed to have atrial fibrillation (AF) either at baseline or new-onset within 30 days after TAVR. Patients with new-onset AF had a >4 fold greater risk of stroke within 30 days. Results from "Effect of bivalirudin versus unfractionated heparin in patients with baseline or new-onset atrial fibrillation in transcatheter aortic valve replacement: From the BRAVO-3 randomized trial" were presented today as a late-breaking clinical trial at the Society for Cardiovascular Angiography and Interventions (SCAI) 2017 Scientific Sessions in New Orleans.
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Analysis looks at role type of valve plays in patient outcomes post-TAVR
For patients who undergo transcatheter aortic valve replacement (TAVR), their risk factors, not the type of valve used, determined their 30-day post-TAVR outcomes. Results from "Impact of valve design and bivalirudin vs. unfractionated heparin for anticoagulation in transcatheter aortic valve replacement: Results from the BRAVO-3 trial" were presented today as a late-breaking clinical trial at the Society for CardiovascularAngiography and Interventions (SCAI) 2017 Scientific Sessions in New Orleans.
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Neurological events with TAVI and surgical valve replacement in intermediate-risk patients
Patients at intermediate risk for surgery have lower risk of early neurological complications including stroke with transcatheter aortic valve implantation (TAVI) than with surgical aortic valve replacement, showed results reported for the first time at EuroPCR 2017 from the large, randomized SURTAVI (Surgical Replacement and Transcatheter Aortic Valve Implantation) trial.
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Nearly one-quarter of patients say mechanical heart valve disturbs sleep
Nearly one-quarter of patients with a mechanical heart valve say it disturbs their sleep, according to research presented today at EuroHeartCare 2017.1
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Study implicates two genetic variants in bicuspid aortic valve development
Researchers are working to determine why the aortic valve doesn't form correctly in patients with the most common congenital heart defect: bicuspid aortic valve.
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Drug developed for arthritis could be first to stop heart valve calcification
The first drug to treat calcification of heart valves may be one originally designed for rheumatoid arthritis.
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Study examines use, outcomes of valve replacement procedure performed for off-label indications
Approximately 1 in 10 transcatheter aortic valve replacement (TAVR) procedures in the U.S. were for an off-label indication, with similar 1-year mortality rates compared to on-label use, suggesting that TAVR may be a possible procedure option for certain patients requiring a heart valve replacement, according to a study published by JAMA Cardiology.
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Fewer infections in mechanical heart valves
Infections in surgically implanted heart valves are more common in patients who have been given a biological prosthetic valve than in those with a mechanical one, a study from Karolinska Institutet published today in the journal Circulation shows.
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Scientists reveal source of human heartbeat in 3-D
A pioneering new study is set to help surgeons repair hearts without damaging precious tissue.
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Which TAVR patients are at risk for hospital readmission? Research identifies new prognostic marker
As more elderly patients undergo the minimally invasive heart valve procedure called Transcatheter Aortic Valve Implantation (TAVR), concerns have been raised as to what causes some to be readmitted for heart failure after the procedure.
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ESC/EACTS Guidelines for the management of valvular heart disease published today
European Society of Cardiology (ESC) / European Association for Cardio-Thoracic Surgery (EACTS) Guidelines for the management of valvular heart disease are published online today in European Heart Journal and on the ESC website.
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Not adhering to recommended exams for severe narrowing of the aortic valve associated with increased heart failure
Patients with asymptomatic severe aortic stenosis who did not follow recommended guidelines for regular exams had poorer survival and were more likely to be hospitalized for heart failure, according to a study published by JAMA Cardiology.
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Study shows low mortality and stroke risks for minimally invasive aortic valve replacements
An analysis of more than 1,000 minimally invasive aortic valve replacements and more than 400 additional associated procedures over a five-and-a-half year period performed by Dr. Joseph Lamelas, professor and associate chief of cardiac surgery in the division of cardiothoracic surgery at Baylor College of Medicine, showed low stroke rates and high survival rates in all age groups within 30 days of surgery. His report appears in the Journal of Thoracic and Cardiovascular Surgery.
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Relatively few kidney patients need to start dialysis after undergoing TAVR
The rate of patients with chronic kidney disease undergoing a heart procedure called transcatheter aortic valve replacement (TAVR) who eventually need to start dialysis is relatively low, suggests a new study published in JACC: Cardiovascular Interventions.
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TAVR cost-effective compared with SAVR in intermediate risk patients with aortic stenosis
Analysis of the PARTNER 2A trial and the SAPIEN-3 Intermediate Risk registry found transcatheter aortic valve replacement (TAVR) to be highly cost-effective compared with surgical aortic valve replacement (SAVR) in intermediate surgical risk patients with aortic stenosis.
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